Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7201450 | 0.85 | SYK (0.31) | — | |
| SCHEMBL7037703 | 0.85 | S1PR1 (0.39) | S1PR1S1PR5 | |
| SCHEMBL7196903 | 0.84 | BRD4 (0.31) | — | |
| SCHEMBL7193885 | 0.83 | S1PR1 (0.33) | S1PR1 | |
| SCHEMBL7035230 | 0.82 | NPC1 (0.32) | S1PR1 | |
| SCHEMBL7035816 | 0.81 | NR3C1 (0.31) | — | |
| SCHEMBL7196689 | 0.81 | S1PR1 (0.32) | S1PR1 | |
| SCHEMBL7198406 | 0.81 | S1PR1 (0.41) | S1PR1S1PR5 | |
| SCHEMBL7037699 | 0.80 | S1PR1 (0.40) | S1PR1S1PR5 | |
| SCHEMBL7031629 | 0.80 | BRS3 (0.36) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |