Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7031629 | 0.93 | BRS3 (0.36) | S1PR1 | |
| SCHEMBL7193885 | 0.91 | S1PR1 (0.33) | S1PR1 | |
| SCHEMBL7037703 | 0.90 | S1PR1 (0.39) | S1PR1 | |
| SCHEMBL7036307 | 0.89 | S1PR1 (0.32) | S1PR1 | |
| SCHEMBL7036446 | 0.88 | S1PR1 (0.32) | S1PR1 | |
| SCHEMBL7037024 | 0.86 | HSD11B1 (0.34) | S1PR1 | |
| SCHEMBL7201450 | 0.85 | SYK (0.31) | — | |
| SCHEMBL7196903 | 0.84 | BRD4 (0.31) | — | |
| SCHEMBL7035816 | 0.84 | NR3C1 (0.31) | — | |
| SCHEMBL7037419 | 0.83 | S1PR1 (0.31) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |