Succinimide

Succinimide

SCHEMBL7039031

CCCCCC.O=C1CCC(=O)N1.O=C1CCC(=O)N1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.61
ALOX5 P09917 2/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
CYP2C19 P33261 1/20 0.42
CYP19A1 P11511 13/20 0.41
ALDH1A1 P00352 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinimide SCHEMBL27423831 1.00 CRBN (0.61) CRBNALOX5KDM4ELMNACYP2C19
Hexadecane SCHEMBL28112342 0.97 CRBN (0.58) CRBNALOX5KDM4ELMNACYP2C19
Dodecane SCHEMBL27509294 0.97 CRBN (0.58) CRBNALOX5KDM4ELMNACYP2C19
Succinimide SCHEMBL4639601 0.94 CRBN (0.61) CRBNALOX5KDM4ELMNACYP2C19
Succinimide SCHEMBL27884254 0.91 CRBN (0.50) CRBNALOX5KDM4ELMNACYP2C19
Succinimide SCHEMBL18205015 0.89 DNM1 (0.50) CRBNALOX5CYP19A1ALDH1A1
Tetrabuthylammonium SCHEMBL2230716 0.89 SLC22A1 (0.52) CRBNALOX5ALDH1A1
Succinimide SCHEMBL22714063 0.88 CRBN (0.69) CRBNALOX5KDM4ELMNACYP2C19
Succinimide SCHEMBL27673277 0.87 CRBN (0.52) CRBNALOX5KDM4ELMNACYP2C19
Succinimide SCHEMBL28234329 0.87 CRBN (0.46) CRBNALOX5LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003004518-A2 CORTISTATIN ANALOGS CAPABLE OF BINDING SELECTIVELY TO GROWTH HORMONE SECRETAGOGUE RECEPTORS ARDANA BIOSCIENCE LIMITED (GB) 2003-01-16 WO disclosed