Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 4/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11789660 | 1.00 | CA2 (0.50) | CA2CA1FDPSCES2CES1 | |
| SCHEMBL1400873 | 0.82 | CA2 (0.54) | CA2CA1FDPSCES2CES1 | |
| SCHEMBL29822627 | 0.82 | CA2 (0.54) | CA2CA1FDPSCES2CES1 | |
| Water SCHEMBL28253140 | 0.80 | CA2 (0.52) | CA2CA1FDPSCES2CES1 | |
| SCHEMBL26685804 | 0.80 | CA2 (0.64) | CA2CA1FDPSCES2CES1 | |
| SCHEMBL17489096 | 0.78 | CA2 (0.50) | CA2CA1FDPSCES2CES1 | |
| SCHEMBL5669736 | 0.78 | CA2 (0.45) | CA2CA1FDPSCES2CES1 | |
| SCHEMBL5669743 | 0.78 | CA2 (0.45) | CA2CA1FDPSCES2CES1 | |
| SCHEMBL1204670 | 0.77 | CA1 (0.58) | CA2CA1FDPSCES2CES1 | |
| SCHEMBL5750240 | 0.75 | FDPS (0.45) | CA2CA1FDPSCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003000251-A1 | NOVEL IDOLINONES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |