Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879317 | 0.87 | BACE1 (0.50) | BACE1PTPN1PTPN2PTPN6PDE4B | |
| SCHEMBL22497560 | 0.82 | LTB4R (0.41) | BACE1PTPN1PTPN2PTPN6PDE4B | |
| SCHEMBL7782075 | 0.82 | LTB4R (0.37) | BACE1PTPN1PTPN2PTPN6PDE4B | |
| SCHEMBL2870986 | 0.81 | BACE1 (0.42) | BACE1PDE4BALDH1A1HPGDKDM4E | |
| SCHEMBL8641643 | 0.81 | CNR1 (0.50) | BACE1PTPN1PTPN2PTPN6PDE4B | |
| SCHEMBL27681638 | 0.80 | BACE1 (0.50) | BACE1PDE4BALDH1A1HPGDKDM4E | |
| SCHEMBL28700316 | 0.78 | BACE1 (0.42) | BACE1PTPN1PTPN2PTPN6PDE4B | |
| SCHEMBL10435692 | 0.78 | BACE1 (0.42) | BACE1ALDH1A1HPGDKDM4EESR2 | |
| SCHEMBL2863890 | 0.78 | HPGD (0.47) | BACE1PDE4BALDH1A1HPGDKDM4E | |
| SCHEMBL7039242 | 0.78 | BACE1 (0.47) | BACE1PDE4BALDH1A1HPGDESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030129409-A1 | Particle and liquid adhesion reduction coating in polycarbonate sheet | GENERAL ELECTRIC COMPANY | 2003-07-10 | — | — | US | disclosed |