Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 5/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039237 | 0.82 | BACE1 (0.45) | LTB4RLTB4R2BACE1AKR1C3AKR1C2 | |
| SCHEMBL22497560 | 0.76 | LTB4R (0.41) | LTB4RLTB4R2BACE1PPARAKDM4E | |
| SCHEMBL2879317 | 0.74 | BACE1 (0.50) | LTB4RLTB4R2BACE1KDM4EALDH1A1 | |
| SCHEMBL28700316 | 0.72 | BACE1 (0.42) | LTB4RLTB4R2BACE1PPARAALDH1A1 | |
| SCHEMBL2870897 | 0.72 | HDAC4 (0.44) | BACE1AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL28424365 | 0.71 | PDE4B (0.42) | LTB4RLTB4R2GCGRBACE1PTPN2 | |
| SCHEMBL27940515 | 0.70 | PDE4B (0.39) | LTB4RLTB4R2GCGRBACE1PDE4B | |
| SCHEMBL5272384 | 0.70 | KMT2A (0.61) | PPARAALDH1A1PPARG | |
| SCHEMBL11022297 | 0.69 | PTPN1 (0.42) | BACE1AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL2870986 | 0.69 | BACE1 (0.42) | LTB4RLTB4R2BACE1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140756-A2 | SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040532-A2 | SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-13 | — | — | WO | disclosed |