Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 7/20 | 0.57 |
| ▸ | ITGB6 | P18564 | 7/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.57 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28804474 | 0.90 | ITGAV (0.56) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL30446650 | 0.87 | ITGAV (0.54) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL7170034 | 0.86 | ITGB3 (0.54) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL25840750 | 0.86 | ITGAV (0.53) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL24341476 | 0.85 | ITGAV (0.52) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL26031769 | 0.83 | ITGAV (0.50) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL26033637 | 0.83 | ITGAV (0.52) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL5856027 | 0.82 | ITGB3 (0.58) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL7172179 | 0.81 | ITGB3 (0.57) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL6589410 | 0.81 | ITGB3 (0.53) | ITGAVITGB6ITGB3ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171304-A1 | Pyridine-2-yl-aminoalkyl carbonyl glycyl-$g(b)-alanine and derivatives thereof | MERCK PATENT GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
| EP-1290010-A1 | PYRIDINE-2-YL-AMINOALKYL CARBONYL GLYCYL-$G(B)-ALANINE AND DERIVATIVES THEREOF | MERCK PATENT GmbH (DE) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096365-A1 | PYRIDINE-2-YL-AMINOALKYL CARBONYL GLYCYL-$G(B)-ALANINE AND DERIVATIVES THEREOF | MERCK PATENT GMBH (DE) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171304-A1 | Pyridine-2-yl-aminoalkyl carbonyl glycyl-$g(b)-alanine and derivatives thereof | GLRB, GLRA3, HAO2 | ITGAV 2128/4885ITGB6 681/4885ITGB3 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.