Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.61 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22388846 | 0.88 | KMT2A (0.76) | RAB9AGAAKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL12348789 | 0.86 | RAB9A (0.65) | RAB9AGAAKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL62930 | 0.85 | PTPN1 (0.90) | RAB9AGAAKMT2APTPN1NPC1 | |
| SCHEMBL20691188 | 0.84 | KMT2A (0.74) | RAB9AGAAKMT2ASMN1; SMN2PKM | |
| SCHEMBL2835923 | 0.83 | PTPN1 (0.81) | RAB9AGAAKMT2APTPN1NPC1 | |
| SCHEMBL20442278 | 0.82 | KMT2A (0.72) | RAB9AGAAKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8660366 | 0.82 | NPC1 (0.83) | RAB9AKMT2APTPN1NPC1SMN1; SMN2 | |
| SCHEMBL6263820 | 0.82 | NPC1 (0.83) | RAB9AKMT2APTPN1NPC1SMN1; SMN2 | |
| Dimethyl Phthalate SCHEMBL7826081 | 0.81 | KMT2A (0.69) | RAB9AGAAKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL22223650 | 0.81 | PTPN1 (0.94) | RAB9AKMT2APTPN1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289936-A1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK, INC. (US) | 2003-03-12 | — | — | EP | disclosed |
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | disclosed |
| WO-2001094295-A1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK, INC. (US) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | SLC2A1, SLC2A8, SLC2A2 | RAB9A 3467/4885GAA 340/4885KMT2A 3788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.