Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039147 | 0.94 | SLC6A2 (0.33) | ATML3MBTL1SMN1; SMN2 | |
| SCHEMBL7040067 | 0.83 | POLB (0.34) | CYP2C9TSHRCYP2C19 | |
| SCHEMBL7035906 | 0.79 | POLB (0.36) | TSHR | |
| SCHEMBL7041307 | 0.72 | FKBP1A (0.35) | — | |
| SCHEMBL14375557 | 0.70 | ATM (0.41) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL3642324 | 0.70 | ATM (0.37) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL11708816 | 0.70 | ATM (0.41) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL9404670 | 0.70 | — | — | |
| SCHEMBL17892416 | 0.69 | LMNA (0.40) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL7041329 | 0.68 | FKBP1A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003000655-A1 | PEROXYKETALS DERIVED FROM CYCLIC Β-KETO ESTERS | CROMPTON CORPORATION (US) | 2003-01-03 | — | — | WO | disclosed |
| US-6362361-B1 | CROSS-LINKING AGENT FOR UNSATURATED POLYESTERS, EPOXY VINYL ESTERS RESINS, ELASTOMERS, THERMOPLASTICS, AND RUBBERS; REDUCED GEL TIMES; REDUCED PRODUCT CRACKING CAUSED BY INTERNAL STRESSES BY LOWERING HEAT EVOLUTION | CROMPTON CORPORATION | 2002-03-26 | — | — | US | disclosed |