SCHEMBL704010

SCHEMBL704010

CC(C)COC(=O)N1CCC([O])CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.51
GAA P10253 1/20 0.46
NOS3 P29474 1/20 0.44
NOS2 P35228 1/20 0.44
THRB P10828 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GPR119 Q8TDV5 2/20 0.42
HSD11B1 P28845 1/20 0.41
KIT P10721 1/20 0.41
CHRM1 P11229 2/20 0.41
CHRM2 P08172 1/20 0.41
ALDH1A1 P00352 1/20 0.40
TLR9 Q9NR96 1/20 0.40
TLR8 Q9NR97 1/20 0.40
TLR7 Q9NYK1 1/20 0.40
JAK2 O60674 1/20 0.40
JAK1 P23458 1/20 0.40
MEN1 O00255 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8262844 0.87 RAB9A (0.50) RAB9AGAANOS3NOS2THRB
SCHEMBL794087 0.87 RAB9A (0.50) RAB9AGAANOS3NOS2THRB
SCHEMBL1563419 0.86 RAB9A (0.49) RAB9AGAANOS3NOS2THRB
SCHEMBL4632551 0.86 RAB9A (0.49) RAB9AGAANOS3NOS2THRB
SCHEMBL13503893 0.86 RAB9A (0.49) RAB9AGAANOS3NOS2THRB
SCHEMBL4633597 0.86 RAB9A (0.49) RAB9AGAANOS3NOS2THRB
SCHEMBL793658 0.86 RAB9A (0.49) RAB9AGAANOS3NOS2THRB
SCHEMBL10089204 0.84 RAB9A (0.48) RAB9AGAANOS3NOS2THRB
SCHEMBL5676009 0.84 RAB9A (0.55) RAB9AGAANOS3NOS2L3MBTL1
SCHEMBL1834064 0.84 RAB9A (0.48) RAB9AGAANOS3NOS2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421852-A1 HETEROAROMATIC AND AROMATIC PIPERAZINYL AZETIDINYL AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITOR Janssen Pharmaceutica N.V. (BE) 2012-02-29 EP claimed
WO-2010124121-A1 HETEROAROMATIC AND AROMATIC PIPERAZINYL AZETIDINYL AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITOR JANSEN PHARMACEUTICA NV (BE) 2010-10-28 WO claimed
EP-2421852-A1 HETEROAROMATIC AND AROMATIC PIPERAZINYL AZETIDINYL AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITOR Janssen Pharmaceutica N.V. (BE) 2012-02-29 EP disclosed
WO-2010124121-A1 HETEROAROMATIC AND AROMATIC PIPERAZINYL AZETIDINYL AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITOR JANSEN PHARMACEUTICA NV (BE) 2010-10-28 WO disclosed