Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704010 | 0.84 | RAB9A (0.51) | RAB9AGAACHRM2CHRM1NOS3 | |
| SCHEMBL794087 | 0.83 | RAB9A (0.50) | RAB9AGAACHRM2CHRM1NOS3 | |
| SCHEMBL8262844 | 0.83 | RAB9A (0.50) | RAB9AGAACHRM2CHRM1NOS3 | |
| SCHEMBL3032184 | 0.82 | GAA (0.61) | GAACHRM1NOS3NOS2THRB | |
| SCHEMBL5249314 | 0.81 | GPR119 (0.45) | RAB9AGAACHRM2CHRM1NOS3 | |
| SCHEMBL793658 | 0.81 | RAB9A (0.49) | RAB9AGAACHRM2CHRM1NOS3 | |
| SCHEMBL13503893 | 0.81 | RAB9A (0.49) | RAB9AGAACHRM2CHRM1NOS3 | |
| SCHEMBL4632551 | 0.81 | RAB9A (0.49) | RAB9AGAACHRM2CHRM1NOS3 | |
| SCHEMBL4633597 | 0.81 | RAB9A (0.49) | RAB9AGAACHRM2CHRM1NOS3 | |
| SCHEMBL1563419 | 0.81 | RAB9A (0.49) | RAB9AGAACHRM2CHRM1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205585-A1 | QUINOLINE DERIVATIVES USED TO TREAT INFLAMMATORY AND ALLERGIC DISEASES | Glaxo Group Limited (GB) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009050204-A1 | QUINOLINE DERIVATIVES USED TO TREAT INFLAMMATORY AND ALLERGIC DISEASES | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |