Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794498 | 0.76 | MMP8 (0.45) | MMP8AKR1B1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL542228 | 0.72 | KDM4E (0.48) | MMP8AKR1B1MAPTKDM4EMETAP1 | |
| SCHEMBL6473838 | 0.72 | KDM4E (0.48) | MMP8AKR1B1MAPTKDM4EMETAP1 | |
| SCHEMBL6473834 | 0.72 | KDM4E (0.48) | MMP8AKR1B1MAPTKDM4EMETAP1 | |
| SCHEMBL27233049 | 0.70 | ALDH1A1 (0.56) | MMP8AKR1B1MAPTALDH1A1KDM4E | |
| SCHEMBL254528 | 0.69 | ALDH1A1 (0.56) | MAPTALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL11695567 | 0.68 | HSD17B10 (0.54) | MAPTALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL7195325 | 0.68 | HSD17B10 (0.54) | MAPTALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL27855209 | 0.67 | HSD17B10 (0.64) | MAPTALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL811522 | 0.66 | ALDH1A1 (0.52) | MAPTALDH1A1L3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003000662-A2 | CHIRAL PREPARATION OF A DIASTEREOMERIC COMPOUND | AVENTIS PHARMACEUTICALS INC. (US) | 2003-01-03 | — | — | WO | disclosed |