Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | EZH2 | Q15910 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8738169 | 0.93 | EZH2 (0.74) | L3MBTL1KMT2AEZH2ALDH1A1LMNA | |
| SCHEMBL169747 | 0.88 | EZH2 (0.80) | L3MBTL1KMT2AEZH2PKMGLA | |
| SCHEMBL8738136 | 0.87 | EZH2 (0.75) | L3MBTL1KMT2AEZH2ALDH1A1LMNA | |
| SCHEMBL11843656 | 0.86 | L3MBTL1 (1.00) | L3MBTL1KMT2AEZH2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11842228 | 0.85 | L3MBTL1 (0.97) | L3MBTL1KMT2AEZH2ALDH1A1LMNA | |
| SCHEMBL7039061 | 0.84 | L3MBTL1 (0.77) | L3MBTL1KMT2AEZH2ALDH1A1LMNA | |
| SCHEMBL14679120 | 0.82 | POLB (0.73) | L3MBTL1KMT2AEZH2GLAPOLB | |
| SCHEMBL6121185 | 0.82 | EZH2 (0.72) | L3MBTL1KMT2AEZH2PKMGLA | |
| SCHEMBL7038879 | 0.82 | GLA (0.70) | L3MBTL1KMT2AEZH2GLAPOLB | |
| SCHEMBL9501495 | 0.81 | MEN1 (0.65) | L3MBTL1KMT2AEZH2ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052248-B1 | Process for the preparation of aqueous solutions of diazonium salts | CLARIANT GMBH (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-6207809-B1 | CATALYTIC HYDROGENATION USING THE CORRESPONDING NITRO COMPOUND | CLARIANT GMBH (DE) | 2001-03-27 | — | — | US | disclosed |
| EP-1052248-A1 | Process for the preparation of aqueous solutions of diazonium salts | Clariant GmbH (DE) | 2000-11-15 | — | — | EP | disclosed |