Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.35 |
| ▸ | PDE5A | O76074 | 5/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040645 | 1.00 | KMT2A (0.36) | KMT2AUSP2PDE4BPDE5APDE3A | |
| SCHEMBL7040647 | 0.87 | MAPT (0.38) | KMT2AUSP2PDE4BPDE5APDE3A | |
| SCHEMBL7109021 | 0.80 | PDE5A (0.36) | KMT2APDE4BPDE5APDE3AL3MBTL1 | |
| SCHEMBL7194688 | 0.79 | PDE5A (0.41) | PDE4BPDE5APDE3AL3MBTL1LMNA | |
| SCHEMBL7194693 | 0.79 | PDE5A (0.41) | PDE4BPDE5APDE3AL3MBTL1LMNA | |
| SCHEMBL7151884 | 0.79 | PDE4B (0.39) | PDE4BPDE5APDE3A | |
| SCHEMBL7034421 | 0.78 | PDE4B (0.40) | KMT2APDE4BPDE5APDE3AMEN1 | |
| SCHEMBL7040393 | 0.77 | PDE5A (0.44) | KMT2APDE4BPDE5APDE3AMEN1 | |
| SCHEMBL7038848 | 0.76 | PDE5A (0.43) | KMT2APDE4BPDE5APDE3AMEN1 | |
| SCHEMBL7109556 | 0.75 | MEN1 (0.43) | KMT2AUSP2PDE4BPDE5APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004494-A1 | PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-16 | — | — | WO | disclosed |