Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 2/20 | 0.54 |
| ▸ | KDM4B | O94953 | 2/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.54 |
| ▸ | KDM5C | P41229 | 1/20 | 0.54 |
| ▸ | GCK | P35557 | 8/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757037 | 0.88 | GCK (0.58) | KDM4AKDM4BKDM5BKDM5CGCK | |
| SCHEMBL4757029 | 0.87 | RAB9A (0.50) | KDM4AKDM4BKDM5BKDM5CGCK | |
| SCHEMBL4757970 | 0.85 | NPC1 (0.65) | KDM4AKDM4BKDM5BKDM5CNPC1 | |
| SCHEMBL703145 | 0.84 | RAB9A (0.60) | NPC1RAB9ATYRHPGDSMN1; SMN2 | |
| SCHEMBL4757279 | 0.84 | RRM1 (0.62) | KDM4AKDM4BKDM5BKDM5CGCK | |
| SCHEMBL706481 | 0.82 | GCK (0.59) | GCKNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL4757285 | 0.79 | RAB9A (0.64) | GCKNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL4757221 | 0.79 | NPC1 (0.48) | GCKNPC1RAB9ATYRHPGD | |
| SCHEMBL4757366 | 0.78 | NPC1 (0.53) | KDM4AKDM4BKDM5BKDM5CGCK | |
| SCHEMBL4757230 | 0.77 | NPC1 (0.41) | KDM4AKDM4BKDM5BKDM5CGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11850237-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2023-12-26 | — | — | US | disclosed |
| US-11850237-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2023-12-26 | — | — | US | disclosed |
| EP-2445349-B1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES LC (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-3895706-A1 | THIAZOLINIDE COMPOUNDS FOR TREATING NON-INFLUENZA VIRAL INFECTIONS | Romark Laboratories, L.C. (US) | 2021-10-20 | — | — | EP | disclosed |
| US-20210177809-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2021-06-17 | — | — | US | disclosed |
| US-10912768-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2021-02-09 | — | — | US | disclosed |
| US-20190307730-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2019-10-10 | — | — | US | disclosed |
| US-10363243-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2019-07-30 | — | — | US | disclosed |
| US-20180078533-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2018-03-22 | — | — | US | disclosed |
| US-20180078533-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2018-03-22 | — | — | US | disclosed |
| US-8124632-B2 | Alkylsulfonyl-substituted thiazolide compounds | ROMARK LABORATORIES, L.C. (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124632-B2 | Alkylsulfonyl-substituted thiazolide compounds | ROMARK LABORATORIES, L.C. (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124632-B2 | Alkylsulfonyl-substituted thiazolide compounds | ROMARK LABORATORIES, L.C. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100330173-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. | 2010-12-30 | — | — | US | disclosed |
| US-20100330173-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. | 2010-12-30 | — | — | US | disclosed |
| EP-2178852-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | Romark Laboratories, L.C. (US) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009035788-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. (US) | 2009-03-19 | — | — | WO | disclosed |
| US-20090036467-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. | 2009-02-05 | — | — | US | disclosed |
| US-20090036467-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. | 2009-02-05 | — | — | US | disclosed |
| US-20090036467-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10912768-B2 | Compounds and methods for treating influenza | HIF1AN, HAVCR2, NEU1 | KDM4A 1429/4885KDM4B 1300/4885KDM5B 1539/4885 |
| US-20180078533-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | KDM4A 1429/4885KDM4B 1300/4885KDM5B 1539/4885 |
| US-20210177809-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | KDM4A 1429/4885KDM4B 1300/4885KDM5B 1539/4885 |
| US-20190307730-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | KDM4A 1429/4885KDM4B 1300/4885KDM5B 1539/4885 |
| US-20100330173-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | KDM4A 1429/4885KDM4B 1300/4885KDM5B 1539/4885 |
| US-11850237-B2 | Compounds and methods for treating influenza | HIF1AN, HAVCR2, NEU1 | KDM4A 1429/4885KDM4B 1300/4885KDM5B 1539/4885 |
| US-10363243-B2 | Compounds and methods for treating influenza | HIF1AN, HAVCR2, NEU1 | KDM4A 1429/4885KDM4B 1300/4885KDM5B 1539/4885 |
| US-20090036467-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | HAVCR2, EIF2AK2, AADAC | KDM4A 2144/4885KDM4B 2750/4885KDM5B 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.