Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385164 | 0.84 | MEN1 (0.70) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7038725 | 0.79 | CYP1A1 (0.66) | MAPTALDH1A1KMT2AMEN1MAOA | |
| SCHEMBL7042043 | 0.79 | MAOA (0.60) | MAPTMAOAROCK2ROCK1CYP1A1 | |
| SCHEMBL12297811 | 0.78 | MAOA (0.47) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL24590383 | 0.78 | ALOX5 (0.62) | MAPTKMT2AMEN1MAOALMNA | |
| Bromide SCHEMBL6833571 | 0.78 | CYP1A1 (0.65) | MAPTALDH1A1KMT2AMEN1MAOA | |
| SCHEMBL12297988 | 0.78 | CYP1A1 (0.56) | MAPTALDH1A1KMT2AMEN1MAOA | |
| Bromide SCHEMBL6833511 | 0.77 | MAOA (0.59) | MAPTMAOAROCK2ROCK1CYP1A1 | |
| SCHEMBL7037764 | 0.76 | MAOA (0.57) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL13341086 | 0.76 | MAOA (0.48) | MAPTALDH1A1KMT2AMEN1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158199-A1 | Novel compounds for inhibition of Tie-2 | KYLIX, B.V. (NL) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158199-A1 | Novel compounds for inhibition of Tie-2 | TIE1, TEK, KDR | MAPT 4149/4885ALDH1A1 1890/4885KMT2A 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.