Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | MC1R | Q01726 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 2/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042432 | 0.84 | NPY1R (0.59) | NPY1RMCHR1NPY5RNPY4RNPFFR1 | |
| SCHEMBL8587073 | 0.80 | PADI4 (0.57) | NPY1RMCHR1 | |
| SCHEMBL7040745 | 0.79 | CA2 (0.49) | NPY1R | |
| SCHEMBL8126399 | 0.78 | MCHR1 (0.55) | NPY1RMCHR1NPY5RNPY4RNPFFR1 | |
| SCHEMBL7037362 | 0.78 | NPY1R (0.50) | NPY1RMCHR1NPY5RNPY4RNPFFR1 | |
| SCHEMBL7039247 | 0.78 | NPY1R (0.53) | NPY1RMCHR1NPY5RNPY4RNPFFR1 | |
| SCHEMBL8665188 | 0.77 | MCHR1 (0.46) | NPY1RMCHR1 | |
| SCHEMBL8528488 | 0.76 | NPY1R (0.62) | NPY1RMCHR1NPY5RNPY4RNPFFR1 | |
| SCHEMBL8126824 | 0.75 | NPY1R (0.63) | NPY1RMCHR1NPY5RNPY4RNPFFR1 | |
| SCHEMBL8120506 | 0.75 | NPY1R (0.63) | NPY1RMCHR1NPY5RNPY4RNPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |