Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 8/20 | 0.57 |
| ▸ | PADI2 | Q9Y2J8 | 6/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042432 | 0.82 | NPY1R (0.59) | NPY1RMCHR1 | |
| SCHEMBL7040969 | 0.80 | NPY1R (0.42) | NPY1RMCHR1 | |
| SCHEMBL8665188 | 0.79 | MCHR1 (0.46) | PADI4NPY1RMCHR1 | |
| SCHEMBL7040745 | 0.78 | CA2 (0.49) | NPY1R | |
| SCHEMBL8639063 | 0.77 | PADI4 (0.65) | PADI4PADI2NPY1RTACR1MCHR1 | |
| SCHEMBL8126399 | 0.77 | MCHR1 (0.55) | PADI4PADI2NPY1RMCHR1 | |
| SCHEMBL7037362 | 0.77 | NPY1R (0.50) | NPY1RMCHR1 | |
| SCHEMBL7039247 | 0.75 | NPY1R (0.53) | NPY1RMCHR1 | |
| SCHEMBL8126824 | 0.74 | NPY1R (0.63) | NPY1RMCHR1 | |
| SCHEMBL8587074 | 0.74 | HDAC1 (0.39) | PADI4PADI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |