SCHEMBL70410

SCHEMBL70410

O=C(Oc1ccccc1)c1ccccc1/C=C/c1ccccc1C(=O)Oc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.61
HPGD P15428 1/20 0.61
ALOX15 P16050 1/20 0.61
MAPT P10636 5/20 0.58
KDM4E B2RXH2 2/20 0.58
TDP1 Q9NUW8 1/20 0.58
ALDH1A1 P00352 7/20 0.49
KMT2A Q03164 4/20 0.47
TSHR P16473 1/20 0.47
LMNA P02545 2/20 0.47
NR4A2 P43354 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CHRM1 P11229 1/20 0.47
TBXA2R P21731 1/20 0.47
SLC6A2 P23975 1/20 0.47
PDE4A P27815 1/20 0.47
ADRA1A P35348 1/20 0.47
KDR P35968 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70411 1.00 HSD17B10 (0.61) HSD17B10HPGDALOX15MAPTKDM4E
Water SCHEMBL28394282 0.88 HSD17B10 (0.53) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL733386 0.87 HSD17B10 (0.59) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL1899108 0.85 HSD17B10 (0.58) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL31590121 0.84 MAPT (0.52) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL69868 0.83 HSD17B10 (0.76) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL29437924 0.83 HSD17B10 (0.76) HSD17B10HPGDALOX15MAPTKDM4E
Phosphine SCHEMBL28084508 0.81 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E
Hydrogen Sulfide SCHEMBL28157119 0.81 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E
Methane SCHEMBL27316738 0.81 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 HSD17B10 2777/4885HPGD 3275/4885ALOX15 1966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.