SCHEMBL733386

SCHEMBL733386

O=Cc1ccccc1C(=O)Oc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.59
HPGD P15428 1/20 0.59
ALOX15 P16050 1/20 0.59
MAPT P10636 5/20 0.56
KDM4E B2RXH2 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
LMNA P02545 4/20 0.52
KMT2A Q03164 3/20 0.52
GAA P10253 1/20 0.52
ALDH1A1 P00352 6/20 0.47
TSHR P16473 1/20 0.46
NR4A2 P43354 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CHRM1 P11229 1/20 0.46
TBXA2R P21731 1/20 0.46
SLC6A2 P23975 1/20 0.46
PDE4A P27815 1/20 0.46
ADRA1A P35348 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70410 0.87 HSD17B10 (0.61) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL70411 0.87 HSD17B10 (0.61) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL28626078 0.86 PTK2B (0.57) HSD17B10HPGDALOX15MAPTLMNA
SCHEMBL5087773 0.86 HSD17B10 (0.57) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL1899108 0.84 HSD17B10 (0.58) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL28626699 0.82 PTGS2 (0.43) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL69868 0.82 HSD17B10 (0.76) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL29437924 0.82 HSD17B10 (0.76) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL733572 0.81 MAPT (0.57) HPGDMAPTKDM4EKMT2AGAA
Hydrogen Sulfide SCHEMBL28157119 0.80 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
EP-1981502-A2 PHARMACEUTICAL COMPOSITION CONTAINING A CENTRAL OPIOID AGONIST, A CENTRAL OPIOID ANTAGONIST, AND A PERIPHERAL OPIOID ANTAGONIST, AND METHOD FOR MAKING THE SAME Harrogate Holdings (BM) 2008-10-22 EP claimed
WO-2007088489-A2 PHARMACEUTICAL COMPOSITION CONTAINING A CENTRAL OPIOID AGONIST, A CENTRAL OPIOID ANTAGONIST, AND A PERIPHERAL OPIOID ANTAGONIST, AND METHOD FOR MAKING THE SAME HARROGATE HOLDINGS (US) 2007-08-09 WO claimed
US-20070185145-A1 Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same HARROGATE HOLDINGS (BM) 2007-08-09 US claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES NATURAL EXTRACTION SYS LLC (US) 2026-02-19 US disclosed
US-12409152-B2 Compositions and methods related to dissolved oxides Natural Extraction Systems, LLC (US) 2025-09-09 US disclosed
US-20250161394-A1 Compositions Comprising Kavalactones NATURAL EXTRACTION SYS LLC (US) 2025-05-22 US disclosed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US disclosed
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FIRST WAVE BIO, INC. 2024-03-07 US disclosed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP disclosed
US-4304833-A DIFFUSION TRANSFER POLAROID CORPORATION (US) 1981-12-08 US disclosed
EP-0032036-A1 Triarylmethane dyes, photographic recording materials, a process in which they are used, and methods for forming triarylmethane dyes POLAROID CORPORATION (US) 1981-07-15 EP disclosed
US-4277407-A LIGHT-SCREENING AGENTS IN COLOR PHOTOGRAPHY POLAROID CORPORATION (US) 1981-07-07 US disclosed
US-3968159-A Process for preparing azomethines MONSANTO COMPANY (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FH, CS, ECHS1 HSD17B10 528/4885HPGD 101/4885ALOX15 460/4885
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB HSD17B10 1788/4885HPGD 533/4885ALOX15 359/4885
US-12409152-B2 Compositions and methods related to dissolved oxides PRKG2, PRKG1, CIT HSD17B10 3658/4885HPGD 317/4885ALOX15 657/4885
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES SCO2, CNR2, CNR1 HSD17B10 1169/4885HPGD 329/4885ALOX15 233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.