Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | HTRA1 | Q92743 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589596 | 0.83 | PREP (0.52) | PREPDRD4GAADPP4DPP7 | |
| SCHEMBL5575952 | 0.83 | PREP (0.52) | PREPDRD4GAADPP4DPP7 | |
| SCHEMBL7418820 | 0.79 | DPP4 (0.40) | PREPDRD4METAP2DPP4DPP7 | |
| SCHEMBL22811264 | 0.77 | ACE (0.57) | PREPDRD4 | |
| SCHEMBL4613460 | 0.76 | NPSR1 (0.60) | PREPKDM4EALDH1A1RAB9A | |
| SCHEMBL7982004 | 0.76 | PREP (0.49) | PREPALDH1A1HTRA1 | |
| SCHEMBL22209509 | 0.76 | PREP (0.51) | PREPDRD4CCR1 | |
| SCHEMBL22209410 | 0.76 | CCR1 (0.57) | PREPTAAR1CCR1 | |
| SCHEMBL18586228 | 0.76 | CCR1 (0.57) | PREPTAAR1CCR1 | |
| SCHEMBL8013574 | 0.75 | TACR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754752-B1 | Dipeptidyl peptidase IV and process for producing the same | AJINOMOTO KK (JP) | 2003-03-26 | — | — | EP | disclosed |
| EP-0754752-A2 | Dipeptidyl peptidase IV and process for producing the same | Ajinomoto Co., Inc. (JP) | 1997-01-22 | — | — | EP | disclosed |