SCHEMBL4613460

SCHEMBL4613460

O=C(NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.60
ALDH1A1 P00352 2/20 0.57
KDM4E B2RXH2 1/20 0.56
LMNA P02545 1/20 0.56
TP53 P04637 1/20 0.56
CTRB1 P17538 1/20 0.56
GFER P55789 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TSHR P16473 3/20 0.55
KMT2A Q03164 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MEN1 O00255 1/20 0.54
KLK7 P49862 1/20 0.53
HDAC1 Q13547 1/20 0.53
KDM1A O60341 1/20 0.52
RCOR1 Q9UKL0 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
CYP2C9 P11712 1/20 0.52
RAB9A P51151 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5264694 0.87 PREP (0.55) NPSR1ALDH1A1KDM4ELMNATP53
SCHEMBL4613461 0.84 NPSR1 (0.73) NPSR1ALDH1A1KDM4ELMNATP53
SCHEMBL3626913 0.83 KDM4E (0.55) NPSR1ALDH1A1KDM4ELMNATP53
SCHEMBL11685811 0.81 CTRB1 (0.64) NPSR1ALDH1A1KDM4ELMNATP53
SCHEMBL7982004 0.81 PREP (0.49) NPSR1ALDH1A1LMNATP53CTRB1
SCHEMBL10589596 0.80 PREP (0.52) KMT2AMEN1HDAC1MAPTRAB9A
SCHEMBL5575952 0.80 PREP (0.52) KMT2AMEN1HDAC1MAPTRAB9A
SCHEMBL18845565 0.80 CTRB1 (0.62) NPSR1ALDH1A1KDM4ELMNATP53
SCHEMBL10222682 0.79 NPSR1 (0.52) NPSR1ALDH1A1KDM4ELMNATP53
SCHEMBL4389585 0.79 NPSR1 (0.66) NPSR1ALDH1A1KDM4ELMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050095660-A1 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women UNIBIO, S.R.I. (IT) 2005-05-05 US claimed
EP-1528396-A1 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women UNIBIO S.R.L. (IT) 2005-05-04 EP claimed
US-20040219617-A1 Enzymatic test for the determination of the risk of pathologies related to the presence of sialidase or prolidase activity in women body fluid samples UNIBIO S.R.L. (IT) 2004-11-04 US claimed
EP-1360484-B1 ENZYMATIC TEST FOR THE DETERMINATION OF THE RISK OF PATHOLOGIES RELATED TO THE PRESENCE OF SIALIDASE OR PROLIDASE ACTIVITY IN WOMEN BODY FLUID SAMPLES UNIBIO S R L (IT) 2008-10-29 EP disclosed
CN-1637150-A Activities and ph tests for the determination of the risk of obstetric and gynecologic complications UNIBIO S R I (IT) 2005-07-13 CN disclosed
US-20050095660-A1 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women UNIBIO, S.R.I. (IT) 2005-05-05 US disclosed
EP-1528396-A1 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women UNIBIO S.R.L. (IT) 2005-05-04 EP disclosed
US-20040219617-A1 Enzymatic test for the determination of the risk of pathologies related to the presence of sialidase or prolidase activity in women body fluid samples UNIBIO S.R.L. (IT) 2004-11-04 US disclosed
EP-0791071-B1 ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES LITMUS CONCEPTS INC (US) 1999-09-15 EP disclosed
EP-0791071-A1 ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES LITMUS CONCEPTS, INC. (US) 1997-08-27 EP disclosed
US-5571684-A SOLID PHASE CONJUGATE LITMUS CONCEPTS, INC. (US) 1996-11-05 US disclosed
WO-1996015255-A2 ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES LITMUS CONCEPTS, INC. (US) 1996-05-23 WO disclosed