SCHEMBL7042345

SCHEMBL7042345

COc1ccc(Nc2cccc3c2C(=O)c2cccc(Nc4ccc(OC)cc4)c2C3=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.59
MAPK1 P28482 5/20 0.59
ALOX12 P18054 1/20 0.59
HSD17B10 Q99714 1/20 0.59
RAB9A P51151 5/20 0.56
ALDH1A1 P00352 5/20 0.56
KDM4E B2RXH2 4/20 0.56
TDP1 Q9NUW8 4/20 0.56
L3MBTL1 Q9Y468 4/20 0.56
HTT P42858 3/20 0.56
LMNA P02545 2/20 0.56
HPGD P15428 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
NSD2 O96028 1/20 0.56
POLB P06746 1/20 0.56
MEN1 O00255 6/20 0.56
KMT2A Q03164 6/20 0.56
P2RY2 P41231 2/20 0.53
P2RY4 P51582 2/20 0.53
CDC25A P30304 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11596912 0.95 MAPT (0.58) MAPTMAPK1ALOX12HSD17B10RAB9A
SCHEMBL11595722 0.88 MAPT (0.53) MAPTMAPK1ALOX12HSD17B10RAB9A
SCHEMBL5273702 0.87 MAPT (0.65) MAPTMAPK1ALOX12HSD17B10RAB9A
SCHEMBL11491441 0.84 P2RY2 (0.55) MAPTMAPK1ALOX12HSD17B10RAB9A
SCHEMBL11593437 0.84 MAPT (0.52) MAPTMAPK1ALOX12HSD17B10RAB9A
SCHEMBL9307069 0.83 MAPT (0.57) MAPTMAPK1RAB9AALDH1A1KDM4E
SCHEMBL9308219 0.83 P2RY4 (0.54) MAPTMAPK1ALOX12HSD17B10RAB9A
SCHEMBL11595639 0.82 MAPT (0.59) MAPTMAPK1RAB9AALDH1A1TDP1
SCHEMBL20334225 0.82 MAPT (0.58) MAPTMAPK1ALOX12HSD17B10RAB9A
SCHEMBL5821140 0.82 EGFR (0.64) MAPTMAPK1ALOX12HSD17B10RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6635350-B2 Having at least one poly(oxyalkylene) chain attached to the 1-position, as well as either the 5- or the 8-position of an anthraquinone backbone MILLIKEN & COMPANY 2003-10-21 US disclosed
US-20030096118-A1 Novel polymeric 1,5- or 1,8-disubstituted anthraquinone-derivative colorants and articles comprising such colorants MILLIKEN & COMPANY 2003-05-22 US disclosed
WO-2003033257-A1 NOVEL POLYMERIC 1,5- OR 1,8-DISUBSTITUTED ANTHRAQUINONE-DERIVATIVE COLORANTS AND ARTICLES COMPRISING SUCH COLORANTS MILLIKEN & COMPANY (US) 2003-04-24 WO disclosed
US-5332521-A Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO., LTD. (JP) 1994-07-26 US disclosed
EP-0352637-B1 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO (JP) 1994-03-30 EP disclosed
US-5200108-A Flexible substrates supporting layer of liquid crystal material and non-liquid crystalline polymer IDEMITSU KOSAN CO., LTD. (JP) 1993-04-06 US disclosed
EP-0352637-A2 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-01-31 EP disclosed
EP-0023780-A1 Silver halide emulsions containing a nucleating agent, photographic elements, film unit and processes for the production of direct positive images EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-02-11 EP disclosed
US-4215030-A Photographic polyester film support FUJI PHOTO FILM CO., LTD. (JP) 1980-07-29 US disclosed
US-4191679-A ANTHRAQUINONE DYES FUJI PHOTO FILM CO., LTD. (JP) 1980-03-04 US disclosed