Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL7042360 | 1.00 | NOTUM (0.43) | NOTUMACP1S1PR1S1PR3TAS2R14 | |
| SCHEMBL1082212 | 0.82 | NOTUM (0.50) | NOTUMACP1S1PR1S1PR3TAS2R14 | |
| SCHEMBL131138 | 0.82 | NOTUM (0.50) | NOTUMACP1S1PR1S1PR3TAS2R14 | |
| SCHEMBL1445873 | 0.79 | NOTUM (0.48) | NOTUMACP1S1PR1S1PR3TAS2R14 | |
| SCHEMBL2095504 | 0.79 | CES2 (0.48) | CES2IDO1 | |
| SCHEMBL29365971 | 0.73 | NOTUM (0.44) | NOTUMACP1S1PR1S1PR3TAS2R14 | |
| SCHEMBL43363 | 0.73 | NOTUM (0.44) | NOTUMACP1S1PR1S1PR3TAS2R14 | |
| SCHEMBL21415457 | 0.73 | NOTUM (0.41) | NOTUMACP1S1PR1S1PR3TAS2R14 | |
| SCHEMBL134690 | 0.71 | TSHR (0.46) | NOTUMACP1S1PR1S1PR3TAS2R14 | |
| SCHEMBL15516021 | 0.71 | NOTUM (0.43) | NOTUMACP1S1PR1S1PR3TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341756-A1 | POLYFLUORINATED AROMATIC OR HETEROCYCLIC DERIVATIVES WITH SULPHURPENTAFLUORIDE GROUP(S) | F2 Chemicals Limited (GB) | 2003-09-10 | — | — | EP | claimed |
| US-20030096999-A1 | Polyfluorinated aromatic or heterocyclic derivatives with sulphurpentalfuoride group(s) | F2 CHEMICALS LIMITED (GB) | 2003-05-22 | — | — | US | claimed |
| WO-2002042263-A1 | POLYFLUORINATED AROMATIC OR HETEROCYCLIC DERIVATIVES WITH SULPHURPENTAFLUORIDE GROUP(S) | F2 CHEMICALS LIMITED (GB) | 2002-05-30 | — | — | WO | claimed |