Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.47 |
| ▸ | NOS1 | P29475 | 9/20 | 0.47 |
| ▸ | NOS3 | P29474 | 6/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033966 | 0.92 | NOS2 (0.57) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5041160 | 0.82 | NOS2 (0.58) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5036602 | 0.81 | NOS2 (0.57) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5036512 | 0.81 | NOS2 (0.57) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL4664600 | 0.81 | NOS2 (0.59) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5036501 | 0.81 | NOS2 (0.70) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5033919 | 0.80 | NOS2 (0.55) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL4134847 | 0.79 | NOS2 (0.52) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| Dimethylamine SCHEMBL5033922 | 0.79 | NOS2 (0.68) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL6871318 | 0.79 | NOS2 (0.44) | NOS2NOS1NOS3CYP2C9FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490366-A1 | NOVEL ALKOXYPYRIDINE-DERIVATIVES | ALTANA Pharma AG (DE) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003080607-A1 | NOVEL ALKOXYPYRIDINE-DERIVATIVES | ALTANA PHARMA AG (DE) | 2003-10-02 | — | — | WO | disclosed |