Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 11/20 | 0.59 |
| ▸ | NOS1 | P29475 | 9/20 | 0.59 |
| ▸ | NOS3 | P29474 | 6/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036501 | 0.91 | NOS2 (0.70) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5041160 | 0.90 | NOS2 (0.58) | NOS2NOS1NOS3CYP2C9PDGFRB | |
| Dimethylamine SCHEMBL5033922 | 0.89 | NOS2 (0.68) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5036602 | 0.89 | NOS2 (0.57) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL5036512 | 0.89 | NOS2 (0.57) | NOS2NOS1NOS3CYP2C9PDGFRB | |
| SCHEMBL5033966 | 0.89 | NOS2 (0.57) | NOS2NOS1NOS3CYP2C9MEN1 | |
| SCHEMBL5036475 | 0.89 | NOS2 (0.54) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL4662911 | 0.89 | NOS2 (0.58) | NOS2NOS1NOS3CYP2C9PDGFRB | |
| SCHEMBL4663083 | 0.88 | NOS2 (0.52) | NOS2NOS1NOS3CYP2C9PDGFRB | |
| SCHEMBL5033919 | 0.88 | NOS2 (0.55) | NOS2NOS1NOS3CYP2C9PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125460-A1 | Imidazopyridine-Derivatives As Inducible No-Synthase Inhibitors | ALTANA PHARMA AG (DE) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125460-A1 | Imidazopyridine-Derivatives As Inducible No-Synthase Inhibitors | PTGS1, PTGIS, NOS1 | NOS2 4/4885NOS1 3/4885NOS3 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.