Terephthalamide

Terephthalamide

SCHEMBL704245

NC(=O)c1ccc(C(N)=O)cc1.NC(=O)c1cccc(C(N)=O)c1.NCCCCCCN

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 9/20 0.52
PARP10 Q53GL7 2/20 0.51
TNKS O95271 1/20 0.51
PARP15 Q460N3 1/20 0.51
PARP14 Q460N5 1/20 0.51
TNKS2 Q9H2K2 1/20 0.51
PARP2 Q9UGN5 1/20 0.51
TSHR P16473 2/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C19 P33261 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL294705 0.96 PARP1 (0.55) PARP1PARP10TNKSPARP15PARP14
Terephthalamide SCHEMBL4193901 0.90 PARP1 (0.57) PARP1PARP10TNKSPARP15PARP14
Terephthalamide SCHEMBL549164 0.88 PARP10 (0.50) PARP1PARP10PARP15PARP14PARP2
Terephthalamide SCHEMBL2427678 0.88 PARP10 (0.50) PARP1PARP10PARP15PARP14PARP2
Terephthalamide SCHEMBL29162705 0.88 PARP10 (0.50) PARP1PARP10PARP15PARP14PARP2
Ethylenediamine SCHEMBL6068910 0.86 PARP1 (0.61) PARP1PARP10TNKSPARP15PARP14
Terephthalamide SCHEMBL5692322 0.85 PARP1 (0.67) PARP1PARP10TNKSPARP15PARP14
SCHEMBL9493945 0.84 PARP1 (0.44) PARP1PARP10TNKSPARP15PARP14
SCHEMBL10458793 0.83 PARP1 (0.64) PARP1PARP10TNKSPARP15PARP14
SCHEMBL12194127 0.82 SMN1; SMN2 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0920476-A1 HIGH PERFORMANCE IONOMER BLENDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-06-09 EP claimed
EP-0881967-A1 SEE-THROUGH FOOD PACKAGING STRUCTURES HAVING A POLYAMIDE FOOD CONTACT-LAYER TO REMOVE COMPOUNDS CAUSING FOOD DISCOLORATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-12-09 EP claimed
WO-1998008901-A1 HIGH PERFORMANCE IONOMER BLENDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-05 WO claimed
WO-1997029910-A1 SEE-THROUGH FOOD PACKAGING STRUCTURES HAVING A POLYAMIDE FOOD CONTACT-LAYER TO REMOVE COMPOUNDS CAUSING FOOD DISCOLORATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-21 WO claimed
EP-1769028-B1 GAS-BARRIER NANOCOMPOSITE COMPOSITION AND ARTICLE USING THE SAME LG CHEMICAL LTD (KR) 2014-09-03 EP disclosed
US-8124681-B2 Golf ball with high moisture barrier properties ACUSHNET COMPANY (US) 2012-02-28 US disclosed
US-20110236703-A1 Coated Metallized Films and Their Method of Manufacture JINDAL FILMS AMERICAS LLC 2011-09-29 US disclosed
EP-1817373-B1 ARTICLE HAVING BARRIER PROPERTY LG CHEMICAL LTD (KR) 2011-06-29 EP disclosed
US-7868080-B2 Gas-barrier nanocomposite composition and article using the same LG CHEM, LTD. (KR) 2011-01-11 US disclosed
US-20100151969-A1 GOLF BALL WITH HIGH MOISTURE BARRIER PROPERTIES JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2010-06-17 US disclosed
WO-2010047891-A1 COATED METALLIZED FILMS AND THEIR METHOD OF MANUFACTURE EXXONMOBIL OIL CORPORATION (US) 2010-04-29 WO disclosed
US-7695381-B1 Golf ball with high moisture barrier properties ACUSHNET COMPANY (US) 2010-04-13 US disclosed
US-5897901-A Method for removing compounds causing discoloration in fruit/vegetables stored in see-through packaging structures E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-04-27 US disclosed
WO-1999012735-A1 PACKAGING MATERIAL E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-18 WO disclosed
US-5877257-A WITH SEMICRYSTALLINE NYLON, AND IONOMERS AND AMORPHOUS NYLON E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-02 US disclosed
EP-0881967-A1 SEE-THROUGH FOOD PACKAGING STRUCTURES HAVING A POLYAMIDE FOOD CONTACT-LAYER TO REMOVE COMPOUNDS CAUSING FOOD DISCOLORATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-12-09 EP disclosed
EP-0848731-A1 ETHYLENE VINYL ALCOHOL COPOLYMER BLENDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-24 EP disclosed
WO-1997029910-A1 SEE-THROUGH FOOD PACKAGING STRUCTURES HAVING A POLYAMIDE FOOD CONTACT-LAYER TO REMOVE COMPOUNDS CAUSING FOOD DISCOLORATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-21 WO disclosed
WO-1997009380-A1 ETHYLENE VINYL ALCOHOL COPOLYMER BLENDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-03-13 WO disclosed
US-5110855-A Packaging E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-05 US disclosed