Terephthalamide

Terephthalamide

SCHEMBL549164

NC(=O)c1ccc(C(N)=O)cc1.NCCCCCCN

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 9/20 0.50
KMT2A Q03164 3/20 0.50
PARP4 Q9UKK3 2/20 0.50
PARP1 P09874 2/20 0.50
TSHR P16473 2/20 0.50
PARP15 Q460N3 2/20 0.50
ALDH1A1 P00352 2/20 0.50
RECQL P46063 2/20 0.50
PARP14 Q460N5 1/20 0.50
PARP16 Q8N5Y8 1/20 0.50
PARP11 Q9NR21 1/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C19 P33261 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL2427678 1.00 PARP10 (0.50) PARP10KMT2APARP4PARP1TSHR
Terephthalamide SCHEMBL29162705 1.00 PARP10 (0.50) PARP10KMT2APARP4PARP1TSHR
Terephthalamide SCHEMBL15066085 0.91 KMT2A (0.46) PARP10KMT2APARP4PARP1TSHR
Terephthalamide SCHEMBL15067352 0.91 KMT2A (0.46) PARP10KMT2APARP4PARP1TSHR
Terephthalamide SCHEMBL704245 0.88 PARP1 (0.52) PARP10KMT2APARP1TSHRPARP15
Terephthalamide SCHEMBL9842217 0.84 PARP10 (0.41) PARP10KMT2APARP4PARP1TSHR
Terephthalamide SCHEMBL8931235 0.84 PARP1 (0.60) PARP10KMT2APARP4PARP1TSHR
SCHEMBL4629493 0.83 ADRA2C (0.41) PARP10KMT2APARP4PARP15ALDH1A1
SCHEMBL28038483 0.83 MAPK1 (0.57) KMT2ATSHRALDH1A1BLMPMP22
SCHEMBL27642188 0.83 PRKACA (0.39) PARP10KMT2APARP4PARP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118076669-A Process for the continuous batch production of polyamides 英威达纺织(英国)有限公司 2024-05-24 CN claimed
US-7820355-B2 Radiation sensitive resin composition ZEON CORPORATION (JP) 2010-10-26 US claimed
US-20240209134-A1 RESIN COMPOSITION, FOAMABLE COMPOSITION, AND CROSSLINKED FOAM BODY KURARAY CO., LTD. (JP) 2024-06-27 US disclosed
WO-2024105929-A1 TALC POWDER, AGENT FOR IMPROVING PROPERTIES OF RESIN, AND RESIN COMPOSITION 林化成株式会社 2024-05-23 WO disclosed
EP-4332136-A1 RESIN COMPOSITION, FOAMABLE COMPOSITION, AND CROSSLINKED FOAM BODY Kuraray Co., Ltd. (JP) 2024-03-06 EP disclosed
EP-4055101-B1 THERMOPLASTIC ELASTOMER COMPOSITION KURARAY CO (JP) 2024-01-03 EP disclosed
US-11787751-B2 Water-absorbent resin and agricultural water-retaining material KURARAY CO., LTD. (JP) 2023-10-17 US disclosed
CN-116635480-A Thermoplastic resin for compression molding 英威达纺织(英国)有限公司 2023-08-22 CN disclosed
US-11692095-B2 Hydrogenated block copolymer, vibration damper, sound insulator, interlayer for laminated glass, dam rubber, shoe sole material, flooring material, laminate, and laminated glass KURARAY CO., LTD. (JP) 2023-07-04 US disclosed
EP-3459994-B1 MOLDED FOAM BODY, DAM RUBBER, COMPOSITE BODY OF DAM RUBBER AND PANEL, AND METHOD FOR INCREASING SOUND TRANSMISSION LOSS KURARAY CO (JP) 2023-02-15 EP disclosed
US-11566129-B2 Thermoplastic elastomer composition KURARAY CO., LTD. (JP) 2023-01-31 US disclosed
EP-0279578-A1 Moldable thermoplastic polyamide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-24 EP disclosed
EP-0270247-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-08 EP disclosed
EP-0270246-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-08 EP disclosed
EP-0262901-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-04-06 EP disclosed
EP-0237187-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-16 EP disclosed
EP-0234819-A2 Thermoplastic resin compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-02 EP disclosed
EP-0191548-A2 High impact resistant polyamide E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-08-20 EP disclosed
EP-0180302-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-05-07 EP disclosed
US-3988287-A WITH AN INORGANIC FILLER; IMPROVED MECHANICAL AND THERMAL PROPERTIES TEIJIN LIMITED (JA) 1976-10-26 US disclosed