Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | USP4 | Q13107 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911331 | 0.85 | CRHBP (0.69) | CRHBPCRHR2TSHRESR1ESR2 | |
| SCHEMBL11627976 | 0.84 | CRHBP (0.52) | CRHBPCRHR2TSHRCTBP2ALDH1A1 | |
| SCHEMBL11375689 | 0.83 | ESR1 (0.58) | CRHBPCRHR2TSHRESR1ESR2 | |
| SCHEMBL16273908 | 0.80 | TSHR (0.67) | TSHRCTBP2OPRK1 | |
| SCHEMBL56760 | 0.78 | ALDH1A1 (0.73) | CTBP2ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL21114396 | 0.77 | CTBP2 (0.54) | CTBP2ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL11460504 | 0.75 | KLK7 (0.64) | CRHBPCRHR2TSHRALDH1A1L3MBTL1 | |
| SCHEMBL7525118 | 0.75 | CRHBP (0.56) | CRHBPCRHR2TSHRESR1ESR2 | |
| SCHEMBL30435086 | 0.74 | HSP90AB1 (0.67) | TSHRCTBP2ALDH1A1MAPK1KMT2A | |
| SCHEMBL979023 | 0.74 | HSP90AB1 (0.67) | TSHRCTBP2ALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011298-A1 | ANTIBACTERIAL OXAZINONES AND METHODS FOR THEIR USE AND SYNTHESIS | CHIROLOGIX PHARMACEUTICALS INC. (CA) | 2003-02-13 | — | — | WO | disclosed |