Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042588 | 0.94 | ADRB3 (0.50) | ADRB3ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL7042719 | 0.91 | ADRB3 (0.51) | ADRB3ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL7044138 | 0.90 | ADRB3 (0.46) | ADRB3ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL7044656 | 0.89 | MEN1 (0.50) | ADRB3ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL7608477 | 0.86 | ADRB3 (0.59) | ADRB3ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL7042688 | 0.85 | ADRB2 (0.45) | ADRB3ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL7042479 | 0.85 | ADRB2 (0.50) | ADRB3ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL7609817 | 0.84 | ADRB3 (0.61) | ADRB3ADRB2ADRB1KMT2AMEN1 | |
| SCHEMBL7251240 | 0.83 | ADRB3 (0.61) | ADRB3ADRB2ADRB1ALDH1A1GAA | |
| SCHEMBL7174716 | 0.82 | ALDH1A1 (0.49) | ADRB3ADRB2ADRB1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292564-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001062705-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-30 | — | — | WO | disclosed |