⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858770 | 0.94 | MEN1 (0.75) | — | |
| Water SCHEMBL2807133 | 0.88 | MEN1 (0.67) | — | |
| Water SCHEMBL1170444 | 0.88 | MEN1 (0.67) | — | |
| Water SCHEMBL199335 | 0.88 | MEN1 (0.67) | — | |
| SCHEMBL7736520 | 0.88 | — | — | |
| SCHEMBL10899688 | 0.88 | — | — | |
| Water SCHEMBL900387 | 0.88 | MEN1 (0.67) | — | |
| Water SCHEMBL6269082 | 0.88 | MEN1 (0.67) | — | |
| Water SCHEMBL148527 | 0.88 | — | — | |
| SCHEMBL5077442 | 0.88 | MEN1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278067-B2 | Encapsulation of plasmid DNA (lipogenes™) and therapeutic agents with nuclear localization signal/fusogenic peptide conjugates into targeted liposome complexes | REGULON, INC. (GR) | 2016-03-08 | — | — | US | disclosed |
| US-20140134232-A1 | Encapsulation of Plasmid DNA (Lipogenes™) and Therapeutic Agents with Nuclear Localization Signal/Fusogenic Peptide Conjugates into Targeted Liposome Complexes | REGULON, INC. (US) | 2014-05-15 | — | — | US | disclosed |
| US-20120183596-A1 | Encapsulation of Plasmid DNA (Lipogenes) and Therapeutic Agents with Nuclear Localization Signal/Fusogenic Peptide Conjugates into Targeted Liposome Complexes | REGULON, INC. | 2012-07-19 | — | — | US | disclosed |
| US-20030072794-A1 | Encapsulation of plasmid DNA (lipogenes™) and therapeutic agents with nuclear localization signal/fusogenic peptide conjugates into targeted liposome complexes | REGULON, INC. | 2003-04-17 | — | — | US | disclosed |
| EP-1292284-A2 | ENCAPSULATION OF POLYNUCLEOTIDES AND DRUGS INTO TARGETED LIPOSOMES | Boulikas, Teni (US) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001093836-A2 | ENCAPSULATION OF POLYNUCLEOTIDES AND DRUGS INTO TARGETED LIPOSOMES | BOULIKAS TENI (US) | 2001-12-13 | — | — | WO | disclosed |