Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL148527 | 1.00 | — | — | |
| Water SCHEMBL2807133 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL15333410 | 1.00 | — | — | |
| Water SCHEMBL900387 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28478211 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28398822 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2590832 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL5858770 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10566608 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL708617 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559855-B2 | Composite substrate, method for producing composite substrate, and method for producing gallium oxide crystal film | NGK INSULATORS, LTD. (JP) | 2026-02-24 | — | — | US | disclosed |
| EP-4628556-A2 | POLISHING METHOD AND POLISHING COMPOSITION | Fujimi Incorporated (JP) | 2025-10-08 | — | — | EP | disclosed |
| CN-114585776-B | Gallium oxide crystal production method | 日本碍子株式会社 | 2025-06-03 | — | — | CN | disclosed |
| US-12163252-B2 | Method for producing an α- or β-gallium oxide crystal by bring an aqueous solution including Ga ions into a supercritical state | NGK INSULATORS, LTD. (JP) | 2024-12-10 | — | — | US | disclosed |
| US-12110422-B2 | Polishing method and polishing composition | FUJIMI INCORPORATED (JP) | 2024-10-08 | — | — | US | disclosed |
| CN-118477667-A | High-activity high-selectivity CO2Co-based intermetallic carbide catalyst for preparing methanol by hydrogenation and preparation method and application thereof | 浙江工业大学 | 2024-08-13 | — | — | CN | disclosed |
| EP-4391083-A2 | COATING LIQUID FOR FORMING N-TYPE OXIDE SEMICONDUCTOR FILM, METHOD FOR PRODUCING N-TYPE OXIDE SEMICONDUCTOR FILM, AND METHOD FOR PRODUCING FIELD-EFFECT TRANSISTOR | Ricoh Company, Ltd. (JP) | 2024-06-26 | — | — | EP | disclosed |
| US-12018401-B2 | Gallium oxide single crystal particle and method for producing the same | NGK INSULATORS, LTD. (JP) | 2024-06-25 | — | — | US | disclosed |
| EP-3350839-B1 | COATING LIQUID FOR FORMING N-TYPE OXIDE SEMICONDUCTOR FILM, METHOD FOR PRODUCING N-TYPE OXIDE SEMICONDUCTOR FILM, AND METHOD FOR PRODUCING FIELD-EFFECT TRANSISTOR | RICOH CO LTD (JP) | 2024-06-12 | — | — | EP | disclosed |
| CN-115155649-B | Heteroatom microporous molecular sieve catalyst, preparation method, application of heteroatom microporous molecular sieve catalyst in isobutene amination and continuous regeneration method | 万华化学集团股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-20060130652-A1 | Adsorbent for adsorption heat pump, adsorbent for humidity-control air conditioner, adsorption heat pump and humidity-control air conditioner | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1610084-A1 | ADSORBENT FOR ADSORPTION HEAT PUMP, ADSORBENT FOR MOISTURE REGULATING CONDITIONER, ADSORPTION HEAT PUMP AND MOISTURE REGULATING CONDITIONER | Mitsubishi Chemical Corporation (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0747339-B2 | Process for production of (poly)alkylene glycol monoalkyl ether | NIPPON CATALYTIC CHEM IND (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0747339-A1 | Process for production of (poly)alkylene glycol monoalkyl ether | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-5380692-A | Pollution control | SAKAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0532024-A1 | Catalyst for catalytic reduction of nitrogen oxide | SAKAI CHEMICAL INDUSTRY CO., LTD., (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0019476-B1 | CATALYST AND PROCESS FOR PRODUCING ORTHO-METHYL SUBSTITUTED PHENOLS USING IT | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1984-01-18 | — | — | EP | disclosed |
| US-4329517-A | COMPRISING IRON OXIDE COMPONENT | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) | 1982-05-11 | — | — | US | disclosed |
| EP-0019476-A2 | Catalyst and process for producing ortho-methyl substituted phenols using it | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1980-11-26 | — | — | EP | disclosed |
| US-4003920-A | OXIDATION OF UNSATURATED HYDROCARBONS | KURARAY CO., LTD. (JA) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559855-B2 | Composite substrate, method for producing composite substrate, and method for producing gallium oxide crystal film | COG2, COPG2, CORO1C | MEN1 1798/4885KMT2A 2561/4885CA5A 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.