Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL148527 | 1.00 | — | — | |
| Water SCHEMBL15333410 | 1.00 | — | — | |
| Water SCHEMBL199335 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL900387 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28478211 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28398822 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2590832 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL5858770 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10566608 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL708617 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122050977-A | Varistor sheet and preparation method thereof | 南阳中威电气有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122028523-A | CuI, alpha-Ga 2O3 pn junction bipolar photoresponsive device and preparation method thereof | 苏州镓和半导体有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-120082047-A | Porous coordination polymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-120037905-A | Pt cluster catalyst, preparation method and application | 陕西氢易能源科技有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119907319-A | Photoconductive solar blind ultraviolet detector based on MgZnO/InGaO heterojunction photosensitive layer and preparation method thereof | 吉林大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119683723-A | Sewage treatment agent and preparation method thereof | 湖北虎鲸智能水产装备研究所有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-115274906-B | Ga is doped based on amorphous In2O3Ultraviolet photoelectric detector of nano material and preparation method thereof | 吉林大学 | 2025-03-07 | — | — | CN | claimed |
| CN-119504444-A | Preparation method of 5-nitrovanillic acid | 浙江工业大学 | 2025-02-25 | — | — | CN | claimed |
| CN-118950014-B | Ni-Co-Cu-Fe-In-M high-entropy intermetallic compound catalyst and preparation method and application thereof | 华东理工大学 | 2025-01-07 | — | — | CN | claimed |
| CN-119143178-A | Preparation of hole transport material based on delafossite quantum dots and application of hole transport material in solar cells | 安徽大学 | 2024-12-17 | — | — | CN | claimed |
| EP-2040718-B1 | GALLIUM NITRATE FORMULATIONS | EMISPHERE TECH INC (US) | 2017-12-27 | — | — | EP | claimed |
| US-9364502-B2 | Gallium nitrate formulations | EMISPHERE TECHNOLOGIES, INC. (US) | 2016-06-14 | — | — | US | claimed |
| US-9345725-B2 | Pharmaceutical formulations of gallium salts | EMISPHERE TECHNOLOGIES, INC. (US) | 2016-05-24 | — | — | US | claimed |
| EP-1830831-B1 | PHARMACEUTICAL FORMULATIONS OF GALLIUM SALTS | EMISPHERE TECH INC (US) | 2015-01-21 | — | — | EP | claimed |
| US-20100239658-A1 | GALLIUM NITRATE FORMULATIONS | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-09-23 | — | — | US | claimed |
| US-20090123562-A1 | Pharmaceutical Formulations of Gallium Salts | EMISPHERE TECHNOLOGIES, INC. (US) | 2009-05-14 | — | — | US | claimed |
| EP-2040718-A2 | GALLIUM NITRATE FORMULATIONS | Emisphere Technologies, Inc. (US) | 2009-04-01 | — | — | EP | claimed |
| WO-2008003050-A2 | GALLIUM NITRATE FORMULATIONS | EMISPHERE TECHNOLOGIES, INC. (US) | 2008-01-03 | — | — | WO | claimed |
| EP-1830831-A2 | PHARMACEUTICAL FORMULATIONS OF GALLIUM SALTS | Emisphere Technologies, Inc. (US) | 2007-09-12 | — | — | EP | claimed |
| WO-2006072070-A2 | PHARMACEUTICAL FORMULATIONS OF GALLIUM SALTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-07-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239658-A1 | GALLIUM NITRATE FORMULATIONS | NOS2, NOS1, SLC6A5 | MEN1 2015/4885KMT2A 4000/4885CA5A 294/4885 |
| US-20090123562-A1 | Pharmaceutical Formulations of Gallium Salts | SLC30A5, SLC35A1, NUP205 | MEN1 968/4885KMT2A 3815/4885CA5A 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.