Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 3/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645612 | 0.89 | MEN1 (0.41) | MEN1KMT2APOLBRAB9AATM | |
| SCHEMBL17867480 | 0.75 | KMT2A (0.51) | MEN1KMT2APOLBRAB9AATM | |
| SCHEMBL1049882 | 0.75 | KDM4E (0.53) | MEN1KMT2APOLBRAB9AATM | |
| Iodide SCHEMBL29227333 | 0.73 | KDM4E (0.51) | MEN1KMT2APOLBRAB9AATM | |
| Hydrochloric Acid SCHEMBL6333076 | 0.73 | KDM4E (0.51) | MEN1KMT2APOLBRAB9AATM | |
| SCHEMBL11004477 | 0.73 | ATM (0.48) | MEN1KMT2APOLBRAB9AATM | |
| SCHEMBL28250926 | 0.73 | MEN1 (0.47) | MEN1KMT2APOLBRAB9AATM | |
| SCHEMBL28816897 | 0.73 | MEN1 (0.44) | MEN1KMT2APOLBRAB9AATM | |
| SCHEMBL4625246 | 0.73 | MEN1 (0.44) | MEN1KMT2APOLBRAB9AATM | |
| Iodide SCHEMBL82245 | 0.73 | ALDH1A1 (0.51) | MEN1KMT2APOLBRAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030021810-A1 | Chlorotoxin inhibition of cell invasion, cancer metastasis, angiogenesis and tissue remodeling | UAB RESEARCH FOUNDATION, THE | 2003-01-30 | — | — | US | disclosed |
| WO-2003000203-A2 | CHLOROTOXIN INHIBITION OF CELL INVASION, CANCER METASTASIS, ANGIOGENESIS AND TISSUE REMODELING | UAB RESEARCH FOUNDATION (US) | 2003-01-03 | — | — | WO | disclosed |