Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1645657 | 0.79 | KMT2A (0.57) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL764729 | 0.77 | KMT2A (0.57) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL7042998 | 0.75 | MEN1 (0.48) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL27874112 | 0.72 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL11395397 | 0.72 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL9645612 | 0.70 | MEN1 (0.41) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL5684840 | 0.69 | HPGD (0.51) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL1128535 | 0.69 | KMT2A (0.97) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL30636590 | 0.69 | KMT2A (0.97) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| Bromide SCHEMBL6228650 | 0.68 | KMT2A (1.00) | KMT2AMEN1ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185725-A1 | c-Met Modulators and Method of Use | EXELIXIS, INC. | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185725-A1 | c-Met Modulators and Method of Use | FLT4, MET, FLT1 | KMT2A 769/4885MEN1 1333/4885ALDH1A1 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.