Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119315 | 0.89 | NPY1R (0.42) | TDP1NPY1RMEN1KMT2ACNR1 | |
| SCHEMBL8527836 | 0.89 | NPY1R (0.43) | TDP1HTR2AHRH1NPY1RMEN1 | |
| SCHEMBL8585368 | 0.88 | NPY1R (0.40) | TDP1HTR2AHRH1NPY1RMEN1 | |
| SCHEMBL1593414 | 0.88 | NPY1R (0.42) | TDP1NPY1RCNR1CNR2NPFFR1 | |
| SCHEMBL8126608 | 0.87 | TDP1 (0.41) | TDP1HTR2AHRH1NPY1RMEN1 | |
| SCHEMBL8112100 | 0.86 | TDP1 (0.44) | TDP1HTR2AHRH1NPY1RMEN1 | |
| SCHEMBL8119409 | 0.86 | EPOR (0.43) | TDP1NPY1RMEN1KMT2ACNR1 | |
| SCHEMBL4650863 | 0.85 | NPY1R (0.40) | NPY1RCNR1CNR2NPFFR1NPFFR2 | |
| SCHEMBL8126197 | 0.85 | NPY1R (0.43) | TDP1NPY1RCNR1CNR2NPFFR1 | |
| SCHEMBL7753050 | 0.85 | NPY1R (0.43) | TDP1NPY1RCNR1CNR2NPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |