Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967943 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1POLB | |
| SCHEMBL24359439 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1POLB | |
| SCHEMBL22014101 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1POLBDRD2DRD3 | |
| SCHEMBL7045053 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1POLBDRD2DRD3 | |
| SCHEMBL13833151 | 0.77 | DRD2 (0.47) | DRD2DRD3PIK3CDDRD4SLC6A3 | |
| SCHEMBL17996818 | 0.77 | DRD2 (0.47) | DRD2DRD3PIK3CDDRD4SLC6A3 | |
| SCHEMBL8860654 | 0.77 | DRD2 (0.47) | DRD2DRD3PIK3CDDRD4SLC6A3 | |
| SCHEMBL5860445 | 0.77 | — | — | |
| SCHEMBL636364 | 0.77 | DRD2 (0.47) | DRD2DRD3PIK3CDDRD4SLC6A3 | |
| SCHEMBL3970694 | 0.77 | DRD2 (0.47) | DRD2DRD3PIK3CDDRD4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717639-B1 | POLYAMINO PARAMAGNETIC CHELATES WHICH CONTAIN BOTH PHOSPHONATE AND NON-PHOSPHONATE MOIETIES FOR MRI | CHELATOR LLC (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-0717639-A4 | POLYAMINO PARAMAGNETIC CHELATES WHICH CONTAIN BOTH PHOSPHONATE AND NON-PHOSPHONATE MOIETIES FOR MRI | CONCAT LTD (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0717639-A1 | POLYAMINO PARAMAGNETIC CHELATES WHICH CONTAIN BOTH PHOSPHONATE AND NON-PHOSPHONATE MOIETIES FOR MRI | CONCAT LTD. (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5409689-A | MRI image enhancement using complexes of paramagnetic cations and amine ligands containing a mixture of phosphonate and non-phosphonate pendant arms | CONCAT, LTD. (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1995005118-A1 | POLYAMINO PARAMAGNETIC CHELATES WHICH CONTAIN BOTH PHOSPHONATE AND NON-PHOSPHONATE MOIETIES FOR MRI | CONCAT LTD. (US) | 1995-02-23 | — | — | WO | disclosed |