Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | EPOR | P19235 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045246 | 0.91 | ITGB3 (0.37) | CNR1ITGB3ITGA2BEPORCNR2 | |
| SCHEMBL7039868 | 0.91 | ITGB3 (0.33) | CNR1ITGB3ITGA2BTDP1MEN1 | |
| SCHEMBL7039838 | 0.90 | TDP1 (0.36) | CNR1ITGB3ITGA2BTDP1RORC | |
| SCHEMBL8118813 | 0.89 | TDP1 (0.36) | CNR1TDP1MEN1KMT2A | |
| SCHEMBL8120991 | 0.86 | F7 (0.36) | CNR1TDP1MEN1KMT2A | |
| SCHEMBL1389118 | 0.82 | CNR1 (0.41) | CNR1TDP1MEN1KMT2AEPOR | |
| SCHEMBL30905434 | 0.82 | CNR1 (0.41) | CNR1TDP1MEN1KMT2AEPOR | |
| SCHEMBL8120339 | 0.82 | BACE1 (0.33) | ITGB3ITGA2B | |
| SCHEMBL7750689 | 0.82 | MEN1 (0.42) | CNR1ITGB3ITGA2BTDP1MEN1 | |
| SCHEMBL9196217 | 0.82 | MEN1 (0.42) | CNR1ITGB3ITGA2BTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |