Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPOR | P19235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043329 | 0.91 | CNR1 (0.35) | ITGB3ITGA2BCNR1CNR2EPOR | |
| SCHEMBL7039868 | 0.88 | ITGB3 (0.33) | ITGB3ITGA2BCNR1HPGDHDAC1 | |
| SCHEMBL8118813 | 0.86 | TDP1 (0.36) | CNR1ALDH1A1 | |
| SCHEMBL8112784 | 0.84 | CNR1 (0.41) | CNR1CNR2HPGDALDH1A1EPOR | |
| SCHEMBL8120991 | 0.83 | F7 (0.36) | CNR1ALDH1A1 | |
| SCHEMBL8127029 | 0.82 | NPY1R (0.41) | CNR1CNR2EPOR | |
| SCHEMBL8122513 | 0.82 | HDAC3 (0.37) | CNR1CNR2HDAC1HDAC7EPOR | |
| SCHEMBL8120085 | 0.82 | CNR1 (0.36) | CNR1CNR2EPOR | |
| SCHEMBL8113179 | 0.82 | CNR1 (0.41) | CNR1CNR2EPOR | |
| SCHEMBL8112714 | 0.81 | MEN1 (0.42) | ITGB3ITGA2BCNR1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |