SCHEMBL7043398

SCHEMBL7043398

C=C(C)C(=O)OCCO.O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
APEX1 P27695 2/20 0.56
HTT P42858 1/20 0.56
KDM4E B2RXH2 2/20 0.42
TSHR P16473 3/20 0.40
CDC25A P30304 1/20 0.40
CDC25B P30305 1/20 0.40
HSD17B10 Q99714 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
RAB9A P51151 2/20 0.38
LMNA P02545 1/20 0.38
ACE2 Q9BYF1 1/20 0.37
THRB P10828 1/20 0.37
PTPN11 Q06124 2/20 0.36
MYC P01106 1/20 0.36
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.36
ELANE P08246 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17800992 0.92 POLB (0.51) POLBTDP1APEX1HTTKDM4E
Pyromellitic Acid SCHEMBL17272685 0.87 POLB (0.47) POLBTDP1APEX1HTTTSHR
SCHEMBL544688 0.86 TDP1 (0.56) POLBTDP1APEX1HTTKDM4E
SCHEMBL31053930 0.86 TDP1 (0.56) POLBTDP1APEX1HTTKDM4E
SCHEMBL543628 0.86 POLB (0.56) POLBTDP1APEX1HTTKDM4E
SCHEMBL17272662 0.85 TDP1 (0.48) POLBTDP1APEX1HTTKDM4E
SCHEMBL345789 0.85 TDP1 (0.61) POLBTDP1APEX1HTTKDM4E
Di(Hydroxyethyl)Ether SCHEMBL18860216 0.84 KDM4E (0.43) POLBTDP1APEX1HTTKDM4E
SCHEMBL837846 0.84 POLB (0.50) POLBTDP1APEX1HTTKDM4E
Phthalic Acid SCHEMBL17184272 0.84 TDP1 (0.48) POLBTDP1APEX1HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040030081-A1 Light diffusing films OMRON CORPORATION (JP) 2004-02-12 US disclosed
EP-1312942-A1 LIGHT DIFFUSING FILMS Omron Corporation (JP) 2003-05-21 EP disclosed