SCHEMBL7043480

SCHEMBL7043480

O=CC(O)(c1ccccc1)c1ccccc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
TDP1 Q9NUW8 2/20 0.42
TSHR P16473 1/20 0.42
KIF11 P52732 1/20 0.39
TRIM24 O15164 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
CYP2C9 P11712 2/20 0.37
KDM4E B2RXH2 3/20 0.36
MMP2 P08253 1/20 0.35
DBH P09172 1/20 0.35
ESR1 P03372 3/20 0.35
ESR2 Q92731 3/20 0.35
CYP3A4 P08684 2/20 0.35
HPGD P15428 4/20 0.34
HSD17B10 Q99714 3/20 0.34
BCL2L1 Q07817 1/20 0.34
CA2 P00918 3/20 0.33
CA4 P22748 3/20 0.33
CA12 O43570 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25432239 0.87 ERN1 (0.40) ALDH1A1TDP1TSHRKIF11TRIM24
SCHEMBL863162 0.81 KDM4E (0.44) ALDH1A1TDP1TSHRCYP2C9KDM4E
SCHEMBL28465786 0.80 KDM4E (0.40) ALDH1A1TDP1TSHRTRIM24TRIM33
SCHEMBL10047426 0.79 MAPT (0.36) ALDH1A1KIF11CYP2C9KDM4ECYP3A4
SCHEMBL811207 0.79 KCNN4 (0.50) KIF11CYP2C9KDM4EL3MBTL1KCNN4
SCHEMBL1628202 0.79 ALDH1A1 (0.41) ALDH1A1TSHRKIF11CYP2C9CYP3A4
SCHEMBL15419956 0.78 ESR2 (0.54) ALDH1A1TDP1TSHRKIF11KDM4E
SCHEMBL26919784 0.75 KDM4E (0.42) ALDH1A1TSHRCYP2C9KDM4EESR1
SCHEMBL28197407 0.74 CYP1A2 (0.40) ALDH1A1TDP1TSHRCYP2C9KDM4E
SCHEMBL25432237 0.73 ALDH1A1 (0.38) ALDH1A1TDP1TSHRKIF11TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003011237-A2 TRANSITION METAL COMPLEXES AS DYE FORMING CATALYSTS IN HAIR COLORING COMPOSITIONS UNILEVER PLC (GB) 2003-02-13 WO disclosed