Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 0.76 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.55 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972108 | 0.92 | LMNA (0.84) | LMNAGAAUSP2ALDH1A1RAB9A | |
| SCHEMBL6621449 | 0.87 | LMNA (0.77) | LMNAGAAUSP2ALDH1A1RAB9A | |
| SCHEMBL15216430 | 0.84 | LMNA (0.73) | LMNAGAAUSP2ALDH1A1RAB9A | |
| SCHEMBL7718022 | 0.84 | LMNA (0.73) | LMNAGAAUSP2ALDH1A1RAB9A | |
| SCHEMBL7047452 | 0.83 | LMNA (0.70) | LMNAGAAUSP2ALDH1A1RAB9A | |
| SCHEMBL2522038 | 0.83 | LMNA (0.70) | LMNAGAAUSP2ALDH1A1RAB9A | |
| SCHEMBL4418697 | 0.82 | LMNA (0.69) | LMNAGAAUSP2ALDH1A1RAB9A | |
| SCHEMBL23367923 | 0.81 | USP2 (0.74) | LMNAGAAUSP2ALDH1A1RAB9A | |
| SCHEMBL6602234 | 0.81 | USP2 (0.69) | LMNAGAAUSP2ALDH1A1POLB | |
| SCHEMBL20301810 | 0.81 | LMNA (0.68) | LMNAGAAUSP2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031567-B1 | THIADIAZOLE CARBOXAMIDE DERIVATIVE, PLANT DISEASE CONTROLLING AGENT, AND METHOD OF USING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| EP-1031567-A1 | THIADIAZOLE CARBOXAMIDE DERIVATIVE, PLANT DISEASE CONTROLLING AGENT, AND METHOD OF USING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2000-08-30 | — | — | EP | disclosed |