Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.58 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.58 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.58 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6621449 | 0.95 | LMNA (0.77) | LMNAALDH1A1GAAUSP2MEN1 | |
| SCHEMBL7718022 | 0.92 | LMNA (0.73) | LMNAALDH1A1GAAUSP2MEN1 | |
| SCHEMBL15216430 | 0.92 | LMNA (0.73) | LMNAALDH1A1GAAUSP2MEN1 | |
| SCHEMBL7043652 | 0.92 | LMNA (1.00) | LMNAALDH1A1GAAUSP2MEN1 | |
| SCHEMBL4418697 | 0.89 | LMNA (0.69) | LMNAALDH1A1GAAUSP2MEN1 | |
| SCHEMBL7043860 | 0.88 | LMNA (0.67) | LMNAALDH1A1GAAUSP2MEN1 | |
| SCHEMBL6814783 | 0.86 | LMNA (0.64) | LMNAALDH1A1GAAUSP2MEN1 | |
| SCHEMBL7042661 | 0.85 | LMNA (0.63) | LMNAALDH1A1GAAUSP2MEN1 | |
| Tiadinil SCHEMBL21573 | 0.84 | KDM4E (0.77) | LMNAALDH1A1GAAUSP2MEN1 | |
| Tiadinil SCHEMBL30553817 | 0.84 | KDM4E (0.77) | LMNAALDH1A1GAAUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313154-B1 | FOR CONTROLLING A PLANT DISEASE | NIHON NOHYAKU CO., LTD. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0930306-A1 | BISTHIADIAZOLE DERIVATIVES AND SALTS THEREOF, DISEASE CONTROLLING AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE, AND METHOD FOR THE USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |