Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928292 | 0.81 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3KCNH2OPRD1 | |
| SCHEMBL10924932 | 0.75 | SLC6A2 (0.36) | SIGMAR1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL10926858 | 0.75 | SIGMAR1 (0.41) | GNAI3GNAO1GNAI1SIGMAR1SLC6A2 | |
| SCHEMBL3576050 | 0.74 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3KCNH2OPRD1 | |
| SCHEMBL9543322 | 0.72 | MAPT (0.34) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7296553 | 0.70 | MAPT (0.32) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10652779 | 0.69 | GNAI3 (0.35) | GNAI3GNAO1GNAI1SIGMAR1HRH2 | |
| SCHEMBL29132530 | 0.69 | SLC6A2 (0.35) | GNAI3GNAO1GNAI1SIGMAR1SLC6A2 | |
| SCHEMBL29132532 | 0.68 | SIGMAR1 (0.37) | GNAI3GNAO1GNAI1SIGMAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL11371125 | 0.68 | GNAI3 (0.33) | GNAI3GNAO1GNAI1SIGMAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289571-B1 | PROCHELATORS OF RADIOMETAL LABELED MOLECULES | UNIV HOSPITAL (CH) | 2004-07-21 | — | — | EP | disclosed |