Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724468 | 0.85 | TLR8 (0.43) | AXLEHMT2ALDH1A1MEN1KMT2A | |
| SCHEMBL266817 | 0.84 | EHMT2 (0.62) | AXLEHMT2IRAK4ALDH1A1MEN1 | |
| SCHEMBL9959290 | 0.81 | AXL (0.52) | AXLEHMT2IRAK4ALDH1A1MEN1 | |
| SCHEMBL29638854 | 0.80 | GPR35 (0.50) | AXLMAOAALDH1A1KDM4ECA12 | |
| SCHEMBL8729103 | 0.80 | GPR35 (0.50) | AXLMAOAALDH1A1KDM4ECA12 | |
| SCHEMBL366714 | 0.80 | GPR35 (0.50) | AXLMAOAALDH1A1KDM4ECA12 | |
| Bromide SCHEMBL8431246 | 0.78 | GPR35 (0.48) | AXLMAOAALDH1A1KDM4ECA12 | |
| SCHEMBL11619589 | 0.78 | AXL (0.49) | AXLEHMT2IRAK4ALDH1A1MEN1 | |
| SCHEMBL298208 | 0.78 | AXL (0.49) | AXLEHMT2IRAK4ALDH1A1MEN1 | |
| SCHEMBL12505510 | 0.78 | EHMT2 (0.55) | AXLEHMT2IRAK4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6238439-B1 | DYEING HAIR WITH IODIDE-FREE, TWO-COMPONENT DYE COMPRISING INDOLE COMPOUND AND AN AQUEOUS ALKALINE OXIDIZER SOLUTION OF HYDROGEN PEROXIDE, UREA PEROXIDE, A PERCARBONATE OR A PERBORATE | L'OREAL (FR) | 2001-05-29 | — | — | US | claimed |
| EP-0597022-B2 | PROCESS FOR THE TEMPORARY DYEING OF KERATIN FIBRES INVOLVING AN INSOLUBLE PIGMENT OBTAINED BY THE OXIDATIVE POLYMERISATION OF INDOLE DERIVATIVES | OREAL (FR) | 1999-11-17 | — | — | EP | claimed |
| US-5874091-A | PROTECTION OF SKIN AND HAIR AGAINST ULTRAVIOLET RADIATION AND FOR PIGMENTATION OF THE SKIN AND HAIR; HOMOGENEOUS AQUEOUS DISPERSION OF LAMELLAR AND ENCAPSULATING VESICLES; STORAGE STABILITY; STORING MELANIN PIGMENT IN THE STRATUM CORNEUM. | L'OREAL (FR) | 1999-02-23 | — | — | US | claimed |
| EP-0587837-B1 | Cosmetic composition containing melanistic pigments in association with certain tocopherols, and method for protecting the skin, the hair, the mucous membranes and cosmetic compositions | OREAL (FR) | 1998-06-03 | — | — | EP | claimed |
| EP-0544874-B1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | OREAL (FR) | 1998-04-08 | — | — | EP | claimed |
| US-5695747-A | APPLYING TO THE SKIN OR HAIR AND ULTRAVIOLET PROETECTION AGENT | L'OREAL (FR) | 1997-12-09 | — | — | US | claimed |
| US-5670099-A | PREPARING A DISPERSION OF LIPIDIC VESICLES FROM ATLEAST ONE LIPID, AN AQUEOUS PHASE ENCAPSULATED IN VESICLE, DISSOLVING POLYMERIZABLE INDOLIC OR INDOLINIC MONOMER WITH A POLYMERIZATION AGENT, REACTS WITH MONOMER FORMS PARTICLES | L'OREAL (FR) | 1997-09-23 | — | — | US | claimed |
| US-5645609-A | Compositions which contain and processes which use an insoluble pigment obtained by the oxidative polymerization of indole derivatives for the temporary dyeing of keratinous fibers | L'OREAL (FR) | 1997-07-08 | — | — | US | claimed |
| EP-0575603-B1 | PRODUCT BASED ON COLOURED MINERAL PARTICLES INCLUDING A MELANIC PIGMENT, PROCESS FOR PREPARING SAME AND APPLICATION IN COSMETICS | OREAL (FR) | 1996-10-23 | — | — | EP | claimed |
| US-5547658-A | Cosmetic composition containing melaninlike pigments in combination with certain tocopherols, and process for protecting the skin, hair, mucosae and cosmetic compositions | L'OREAL (FR) | 1996-08-20 | — | — | US | claimed |
| US-5205837-A | Formed in situ by oxidation of indole compound | L'OREAL (FR) | 1993-04-27 | — | — | US | claimed |
| WO-1993002655-A1 | PROCESS FOR THE TEMPORARY DYEING OF KERATIN FIBRES INVOLVING AN INSOLUBLE PIGMENT OBTAINED BY THE OXIDATIVE POLYMERISATION OF INDOLE DERIVATIVES | L'OREAL (FR) | 1993-02-18 | — | — | WO | claimed |
| WO-1993000068-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-01-07 | — | — | WO | claimed |
| EP-0518773-A1 | Cosmetic composition containing a blend of metallic oxids nanopigments and melanic pigments | L'OREAL (FR) | 1992-12-16 | — | — | EP | claimed |
| EP-0504347-A1 | COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS. | OREAL (FR) | 1992-09-23 | — | — | EP | claimed |
| WO-1992005761-A1 | COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS | L'OREAL (FR) | 1992-04-16 | — | — | WO | claimed |
| EP-0467767-A1 | Product based on flaky particles containing melanine pigment and process for their preparation | L'OREAL (FR) | 1992-01-22 | — | — | EP | claimed |
| EP-0462883-A1 | Keratinous fibres dyeing process with indols, compositions and devices | L'OREAL (FR) | 1991-12-27 | — | — | EP | claimed |
| EP-0446132-A1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |