Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043689 | 0.85 | AXL (0.49) | AXLMAPTPOLBMEN1KMT2A | |
| SCHEMBL1545052 | 0.85 | TLR8 (0.54) | TLR8TLR7BACE1MAPTAPP | |
| SCHEMBL1959555 | 0.82 | POLB (0.50) | TLR8TLR7BACE1MAPTAPP | |
| SCHEMBL10438327 | 0.77 | GPR35 (0.58) | BACE1MAPTPOLBMEN1KMT2A | |
| SCHEMBL4420798 | 0.76 | CYP2A6 (0.46) | AXLPOLBMEN1KMT2AMAPK1 | |
| SCHEMBL8729103 | 0.75 | GPR35 (0.50) | AXLMAPTKDM4EALDH1A1CA12 | |
| SCHEMBL29638854 | 0.75 | GPR35 (0.50) | AXLMAPTKDM4EALDH1A1CA12 | |
| SCHEMBL366714 | 0.75 | GPR35 (0.50) | AXLMAPTKDM4EALDH1A1CA12 | |
| Bromide SCHEMBL8431246 | 0.74 | GPR35 (0.48) | AXLMAPTKDM4EALDH1A1CA12 | |
| SCHEMBL31375351 | 0.73 | TYR (0.58) | POLBMEN1KMT2AMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167669-A | Hair dyes | L'OREAL (FR) | 1992-12-01 | — | — | US | disclosed |