Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049831 | 0.84 | ALDH1A1 (0.42) | EGFRPDK2ALDH1A1L3MBTL1GAA | |
| SCHEMBL7048279 | 0.82 | EGFR (0.33) | EGFRALDH1A1GAAKMT2ADYRK1A | |
| SCHEMBL7050655 | 0.81 | CA1 (0.35) | EGFRPDK2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7049632 | 0.81 | EGFR (0.33) | EGFRPDK2ALDH1A1DYRK1A | |
| SCHEMBL7046506 | 0.81 | CA1 (0.35) | EGFRPDK2ALDH1A1DYRK1A | |
| SCHEMBL29619668 | 0.78 | EGFR (0.40) | EGFRALDH1A1MAPTGAAKMT2A | |
| SCHEMBL255284 | 0.78 | EGFR (0.40) | EGFRALDH1A1MAPTGAAKMT2A | |
| SCHEMBL7047198 | 0.77 | MEN1 (0.40) | ADORA2AEGFRPDK2ALDH1A1MAPT | |
| SCHEMBL7049849 | 0.74 | MAPT (0.49) | PTPRCALDH1A1L3MBTL1MAPTGAA | |
| SCHEMBL7050129 | 0.73 | PDK2 (0.40) | PDK2ALDH1A1L3MBTL1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | disclosed |