Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018645 | 0.81 | GPR119 (0.38) | CNR2HDAC6 | |
| SCHEMBL6018647 | 0.81 | GPR119 (0.38) | CNR2HDAC6 | |
| SCHEMBL15017085 | 0.79 | CNR2 (0.38) | CNR2HDAC6 | |
| SCHEMBL5762532 | 0.78 | CNR2 (0.35) | CNR2HDAC6 | |
| SCHEMBL5762536 | 0.78 | CNR2 (0.35) | CNR2HDAC6 | |
| SCHEMBL5763983 | 0.77 | NR1H2 (0.32) | CNR2 | |
| SCHEMBL5763985 | 0.77 | NR1H2 (0.32) | CNR2 | |
| SCHEMBL6018462 | 0.77 | KDM1A (0.33) | CNR2HDAC6 | |
| SCHEMBL6018468 | 0.77 | KDM1A (0.33) | CNR2HDAC6 | |
| SCHEMBL20176953 | 0.75 | CNR2 (0.34) | CNR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456171-A1 | SUBSTITUTED CYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053919-A1 | SUBSTITUTED CYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA-ROCHE AG (CH) | 2003-07-03 | — | — | WO | disclosed |