SCHEMBL7044064

SCHEMBL7044064

CCc1ccc2sc3ccc(CC)cc3c(=O)c2c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 3/20 0.45
MAPT P10636 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
PIM1 P11309 1/20 0.45
PIM2 Q9P1W9 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
MTNR1A P48039 3/20 0.39
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
TRPA1 O75762 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29422893 0.91 KDM4E (0.58) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL166961 0.91 KDM4E (0.58) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL28586486 0.87 NPC1 (0.44) NPC1RAB9AALDH1A1MAPTL3MBTL1
SCHEMBL29694182 0.82 PIM1 (0.43) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL215977 0.82 PIM1 (0.43) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL11632495 0.82 CYP2A6 (0.44) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL11632024 0.82 ALDH1A1 (0.46) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL6860677 0.80 ALDH1A1 (0.50) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL10889406 0.80 SMN1; SMN2 (0.39) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL15500071 0.78 NPC1 (0.42) NPC1RAB9AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962826-A1 A positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-08 EP claimed
US-20170351147-A1 LAMINATE AND OPTICAL FILM FUJIFILM CORPORATION (JP) 2017-12-07 US disclosed
US-20170351147-A1 LAMINATE AND OPTICAL FILM FUJIFILM CORPORATION (JP) 2017-12-07 US disclosed
US-7785676-B2 Optical compensation sheet, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-08-31 US disclosed
US-7785676-B2 Optical compensation sheet, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-08-31 US disclosed
US-20090122233-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-05-14 US disclosed
US-20090122233-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-05-14 US disclosed
WO-2007049814-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-05-03 WO disclosed
US-6815140-B2 COMPRISING A NOVOLAC RESIN, A RADIATION-SENSITIVE QUINONEDIAZIDE COMPOUND, AND ALSO A THIOXANTHONE COMPOUND TO IMPROVE RESOLUTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
EP-0962826-A1 A positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-08 EP disclosed