Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1448057 | 0.96 | PTPN1 (0.66) | PTPN1HPGDLMNAMEN1KMT2A | |
| SCHEMBL693169 | 0.95 | PTPN1 (0.69) | PTPN1HPGDLMNAMEN1KMT2A | |
| SCHEMBL883845 | 0.92 | NAMPT (0.61) | PTPN1HPGDLMNAMEN1KMT2A | |
| SCHEMBL15528879 | 0.84 | SIRT2 (0.52) | PTPN1HPGDLMNAMEN1KMT2A | |
| SCHEMBL5198248 | 0.84 | ALDH1A1 (0.51) | PTPN1HPGDLMNAMEN1KMT2A | |
| SCHEMBL1353592 | 0.82 | PKM (0.55) | PTPN1LMNANAMPTRAB9AMAPT | |
| SCHEMBL2184247 | 0.81 | HPGD (0.89) | PTPN1HPGDLMNAMEN1KMT2A | |
| SCHEMBL28930205 | 0.80 | NAMPT (0.53) | PTPN1HPGDLMNAMEN1KMT2A | |
| SCHEMBL28656982 | 0.80 | PTPN1 (0.89) | PTPN1HPGDLMNAMEN1KMT2A | |
| SCHEMBL125695 | 0.80 | PTPN1 (0.89) | PTPN1HPGDLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | claimed |